USC vs. Notre Dame spread, odds, props, line: College football picks, bets, prediction by expert on 19-6 run

Reigning Heisman Trophy winner Caleb Williams and the No. 10 USC Trojans (6-0) glance to stay their best possible document in tact once they go back and forth to South Bend, Ind. to take on the No. 21 Notre Dame Fighting Irish (5-2) on Saturday. The Trojans are coming off a 43-41 triple extra time win over Arizona, whilst Notre Dame is taking a look to bop again from a 33-20 loss to Louisville. The competition between USC and Notre Dame is among the maximum storied within the historical past of school football, with the Irish retaining a bonus, successful 4 of the final 5 conferences and retaining a 48–37–5 edge within the all-time collection. 

Kickoff is ready for 7:30 p.m. ET on Saturday at Notre Dame Stadium in South Bend. The Huskies are preferred by 3 issues in the newest USC vs. Notre Dame odds, whilst the over/beneath is ready at 60.5 issues, in keeping with SportsLine consensus. Before making any Notre Dame vs. USC selections or bets, be sure to check out the college football predictions and betting advice from SportsLine football expert Jimmie Kaylor. 

Kaylor is a NFL, school football, and DFS expert for SportsLine, who has coated the NFL and faculty football for on the subject of a decade as a member of the Pro Football Writers of America. His background as a former school football All-American and NFL participant provides him a singular viewpoint when construction his myth lineups and locking in his having a bet selections. He has his finger on the heartbeat of the school football panorama and has been cashing in giant for the final two years. 

Kaylor has been red-hot on his football selections for SportsLine in 2023, going 19-6 on his absolute best bets, together with a 5-1 mark within the USC-Colorado recreation, up up to now within the season. Anyone who has adopted his selections is much up.

Now, he has set his points of interest on USC vs. Notre Dame and simply locked in its selections and CFB predictions. You can head to SportsLine now to see Kaylor’s picks. Here are a number of college football odds and having a bet traces for Notre Dame vs. USC:

• Notre Dame vs. USC unfold: Notre Dame -3
• Notre Dame vs. USC over/beneath: 60.5 issues
• Notre Dame vs. USC cash line: USC +118, Notre Dame -140
• USC: QB Caleb Williams leads school football with 22 TD passes.
• ND: The Irish have gained 4 of the final 5 conferences with USC.
• Notre Dame vs. USC selections: See picks at SportsLine
• Notre Dame vs. USC are living move: fubo (take a look at totally free)

Why USC can quilt

The Trojans have arguably the most productive participant in school football in quarterback Caleb Williams. The reigning Heisman Trophy winner has been exceptional in his 2d season guiding the Trojans, and his the power to stay his group in each and every recreation they play. Williams enters this matchup finishing 71.7% of his passes for 1,822 yards, 22 landing passes, and one interception. He’s additionally rushed for 124 yards and 6 TDs.

Running again MarShawn Lloyd has been a dynamic danger out of the backfield that may take some power off of Williams. The 210-pound junior enters this matchup averaging 7.7 yards in keeping with lift. In overall, Lloyd has 519 yards and 4 touchdowns. In USC’s win over Arizona, Lloyd completed with 86 yards and a TD on 15 carries. See which team to pick at SportsLine. 

Why Notre Dame can quilt

Notre Dame is skilled with strengths on all sides of the ball. Transfer quarterback Sam Hartman has been exceptional in his first season in South Bend, finishing 64.5% of his passes for 1,712 yards, 16 touchdowns, and 3 interceptions. He’s additionally scored two TDs on the bottom. Hartman provides the Irish the primary game-changing participant on the quarterback place in different years.

Running again Audric Estime has performed at a prime degree all season for Notre Dame and will likely be tough for USC’s porous protection to include. The 227-pound junior is a real three-down operating again having the ability to run between the tackles and catch passes out of the backfield. Estime enters this matchup with 105 carries for 692 yards (8.9 yards in keeping with lift) and 7 touchdowns. He has additionally stuck 10 passes for 89 yards. See which team to back at SportsLine.

How to make Notre Dame vs. USC selections

Kaylor has analyzed this matchup from each and every attitude and he is leaning Over on the purpose overall. He has additionally came upon a essential X-factor that has him leaping in every single place one facet of the unfold. He’s only sharing what it is, and which side to back, at SportsLine.

Who wins USC vs. Notre Dame on Saturday, and which essential X-factor makes one facet of the unfold a must-back? Visit SportsLine now to see Notre Dame vs. USC picks, all from the expert who has covered college football for over a decade and is 19-6 on his best bets in 2023, and in finding out.