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Physical activity may have a stronger role than genes in longevity — ScienceDaily


Previous analysis has proven that low bodily activity and larger time spent sitting are related to a larger danger of demise. Does danger change if a individual is genetically predisposed to reside a lengthy life?

That is the query researchers on the Herbert Wertheim School of Public Health and Human Longevity Science at University of California San Diego got down to reply in a examine printed in the August 24, 2022 on-line version of the Journal of Aging and Physical Activity.

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“The goal of this research was to understand whether associations between physical activity and sedentary time with death varied based on different levels of genetic predisposition for longevity,” stated lead writer Alexander Posis, M.P.H., a fourth-year doctoral scholar in the San Diego State University/UC San Diego Joint Doctoral Program in Public Health.

In 2012, as a part of the Women’s Health Initiative Objective Physical Activity and Cardiovascular Health examine (OPACH), researchers started measuring the bodily activity of 5,446 girls in the United States who have been 63 and older, following them via 2020 to find out mortality. Participants wore a research-grade accelerometer for as much as seven days to measure how a lot time they spent transferring, the depth of bodily activity, and sedentary time.

The potential examine discovered that larger ranges of sunshine bodily activity and moderate-to-vigorous bodily activity have been related to decrease danger of demise. Higher sedentary time was related to larger danger of mortality. These associations have been constant amongst girls who had completely different ranges of genetic predisposition for longevity.

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“Our study showed that, even if you aren’t likely to live long based on your genes, you can still extend your lifespan by engaging in positive lifestyle behaviors such as regular exercise and sitting less,” stated senior writer Aladdin H. Shadyab, Ph.D., assistant professor on the Herbert Wertheim School of Public Health and Human Longevity Science at UC San Diego. “Conversely, even if your genes predispose you to a long life, remaining physically active is still important to achieve longevity.”

Given the growing older grownup inhabitants in the United States, and longer time spent participating in decrease depth actions, the examine findings assist suggestions that older girls ought to take part in bodily activity of any depth to cut back the chance of illness and untimely demise, wrote the authors.

The OPACH Study is funded by the National Heart, Lung, and Blood Institute (RO1 HL105065). Funding additionally got here from the National Institute on Aging (P01 AG052352) and a T32 Predoctoral Training Fellowship (T32 AG058529). The Women’s Health Initiative was funded by the National Heart, Lung, and Blood Institute (75N92021-D00001, 75N92021D00002, 75N92021D00003, 75N92021D00004, 75N92021D00005).

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Materials offered by University of California – San Diego. Original written by Yadira Galindo. Note: Content may be edited for fashion and size.



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