Monday, May 6, 2024

Oklahoma foundation studying aging and muscle loss

OKLAHOMA CITY (KFOR) – Researchers in Oklahoma say they’re planning to review how aging impacts the physique’s muscular system.

The National Institutes of Health awarded the Oklahoma Medical Research Foundation $3.4 million to review age-related muscle atrophy and weak spot.

OMRF scientists say they realized that some age-related muscle loss is definitely related to a lacking nerve sign.

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Most folks start to expertise progressive loss of muscle mass and power of their 30s or 40s. However, the situation turns into extra pronounced after 65, making each day duties tough for some folks.

“It’s just a natural process of aging, and some people lose more muscle mass and strength than others,” mentioned Jacob Brown, Ph.D.

While inactivity is the commonest contributor to muscle loss, the crew discovered that denervation is one other trigger.

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Denervation is an interruption in communication with the nerves that join muscle tissue to the spinal wire.

With the brand new grant, the researchers will research whether or not blocking the manufacturing of the metabolite protects in opposition to age-related muscle atrophy.

“This is a novel area of research that we hope will lead to new possibilities to design much-needed pharmaceutical interventions,” mentioned Holly Van Remmen, who holds the G.T. Blankenship Chair in Aging Research. “Ultimately, we hope this path of research will extend the time that older adults can remain healthy and active.”

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Researchers say older adults can keep off muscle loss by staying bodily energetic and sustaining a nutritious diet.

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