Monday, April 29, 2024

NCI grants $5 million to UTHealth Houston for cancer control research in Mexico and Latin America


A five-year, $5 million grant has been awarded through the National Cancer Institute (NCI) to the UTHealth Houston Institute for Implementation Science to strengthen research and coaching in implementation science, with a focal point on making improvements to cancer control efforts in Mexico and Latin America.

The grant brings in combination researchers from UTHealth Houston, the Mexican National Institute of Public Health (INSP), the Mexican National Cancer Institute (INCan), and the University of California San Francisco (UCSF).

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The grant will fund a brand new heart, LISTOS for Cancer Control – Leveraging Implementation Science To Optimize Strategies for Cancer Control. The a couple of foremost investigators are María E. Fernández, PhD, vice chairman of inhabitants well being and implementation science at UTHealth Houston and co-director of the Institute for Implementation Science; Martin Lajous, MD, DSc, faculty-researcher in the Center for Research in Population Health at INSP; and Karla Unger, MD, DSc, researcher in the Department of Epidemiology at INCan.

This collaborative heart objectives to bridge the distance between evidence-based cancer prevention and control interventions and their real-world implementation. It will even empower native pros to use implementation science to beef up cancer control fairness in Mexico and Latin America. We watch for that the affect of this heart can have an enduring impact on addressing those problems for years to come.”


María E. Fernández, the Lorne Bain Chair in Public Health and Medicine and professor in the Department of Health Promotion at UTHealth Houston School of Public Health

LISTOS is likely one of the 4 facilities decided on through the NCI, a part of the National Institutes of Health, below the Global Implementation Science for Equitable Cancer Control investment alternative. Its number one challenge is to bolster research capability for implementation science in low- and middle-income nations and to facilitate research that identifies, comprehends, and overcomes stumbling blocks to the adoption, adaptation, integration, dissemination, and sustainability of evidence-based cancer control interventions in those nations. Notably, LISTOS is the only web site devoted to bettering cancer control in the Latin American and Caribbean area.

Researchers will take on vital cancer-related disparities through designing and checking out new implementation methods which can be culturally related and are compatible the native context. Additionally, they are going to advance the sphere of implementation science in Latin America through offering coaching, mentorship, and different enticing actions to foster the following technology of implementation science leaders.

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The preliminary segment of the LISTOS Center will come with two research aimed toward bettering early cancer detection inside of well being care programs. The findings from those research will give a contribution to cutting edge methods that strengthen the long-term implementation of colorectal cancer screening and the mixing of speedy breast cancer analysis.

“In low- and middle-income countries, there is much that can be done to improve cancer control, yet the translation of evidence-based interventions into real-world practice lags behind what we know works. Our research aims to enhance cancer control in the region, reducing the burden of breast cancer and bolstering prevention and early detection of colorectal cancer,” Lajous mentioned.

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The function of the colorectal cancer screening venture is to adapt evidence-based interventions (affected person schooling, affected person reminders, and affected person navigation), design implementation methods to ship those interventions, and evaluation the effectiveness, cost-effectiveness, and implementation results. This venture will happen in Mexico’s publicly funded well being device for folks with social safety. The breast cancer research venture seeks to expand and check implementation methods designed to make stronger built-in care for speedy breast cancer analysis throughout quite a lot of ranges of the well being care device, specifically for girls presenting with breast signs in number one care settings. This venture will likely be applied inside of Mexico’s public well being device available to the uninsured inhabitants.

“LISTOS will allow us to partner with local health systems to develop laboratories for innovation in cancer screening and early diagnosis and demonstrate both clinical and implementation outcomes that can be replicated nationally in Mexico,” mentioned Michael Potter, MD, with UCSF, who’s co-lead investigator of the colorectal screening learn about and a member of the LISTOS Executive Committee.

The LISTOS Center may be running with Leticia Torres Ibarra, DSc, with INSP; and Olga Martínez, MD, MPH, of the Mexican Institute of Social Security on a pilot venture to learn about implementation of an ongoing program to make stronger human papilloma virus checking out amongst girls running in factories and inns.

“Due to a highly segmented health care model and insufficient evidence on effective implementation strategies, populations in low- to middle-income countries are disproportionately impacted by cancer compared to those in higher-income countries. Our center and the studies we conduct will help address these issues and contribute to the science of implementation in these countries that can be applied to many other health issues,” Unger mentioned.

The NIH investment is below grant U54CA284109.

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A five-year, $5 million grant has been awarded through the National Cancer Institute (NCI) to the UTHealth Houston Institute for Implementation Science to strengthen research and coaching in implementation science, with a focal point on making improvements to cancer control efforts in Mexico and Latin America.

The grant brings in combination researchers from UTHealth Houston, the Mexican National Institute of Public Health (INSP), the Mexican National Cancer Institute (INCan), and the University of California San Francisco (UCSF).

The grant will fund a brand new heart, LISTOS for Cancer Control – Leveraging Implementation Science To Optimize Strategies for Cancer Control. The a couple of foremost investigators are María E. Fernández, PhD, vice chairman of inhabitants well being and implementation science at UTHealth Houston and co-director of the Institute for Implementation Science; Martin Lajous, MD, DSc, faculty-researcher in the Center for Research in Population Health at INSP; and Karla Unger, MD, DSc, researcher in the Department of Epidemiology at INCan.

“This collaborative center aims to bridge the gap between evidence-based cancer prevention and control interventions and their real-world implementation,” mentioned Fernández, the Lorne Bain Chair in Public Health and Medicine and professor in the Department of Health Promotion at UTHealth Houston School of Public Health. “It will also empower local professionals to use implementation science to enhance cancer control equity in Mexico and Latin America. We anticipate that the impact of this center will have a lasting effect on addressing these issues for years to come.”

LISTOS is likely one of the 4 facilities decided on through the NCI, a part of the National Institutes of Health, below the Global Implementation Science for Equitable Cancer Control investment alternative. Its number one challenge is to bolster research capability for implementation science in low- and middle-income nations and to facilitate research that identifies, comprehends, and overcomes stumbling blocks to the adoption, adaptation, integration, dissemination, and sustainability of evidence-based cancer control interventions in those nations. Notably, LISTOS is the only web site devoted to bettering cancer control in the Latin American and Caribbean area.

Researchers will take on vital cancer-related disparities through designing and checking out new implementation methods which can be culturally related and are compatible the native context. Additionally, they are going to advance the sphere of implementation science in Latin America through offering coaching, mentorship, and different enticing actions to foster the following technology of implementation science leaders.

The preliminary segment of the LISTOS Center will come with two research aimed toward bettering early cancer detection inside of well being care programs. The findings from those research will give a contribution to cutting edge methods that strengthen the long-term implementation of colorectal cancer screening and the mixing of speedy breast cancer analysis.

“In low- and middle-income countries, there is much that can be done to improve cancer control, yet the translation of evidence-based interventions into real-world practice lags behind what we know works. Our research aims to enhance cancer control in the region, reducing the burden of breast cancer and bolstering prevention and early detection of colorectal cancer,” Lajous mentioned.

The function of the colorectal cancer screening venture is to adapt evidence-based interventions (affected person schooling, affected person reminders, and affected person navigation), design implementation methods to ship those interventions, and evaluation the effectiveness, cost-effectiveness, and implementation results. This venture will happen in Mexico’s publicly funded well being device for folks with social safety. The breast cancer research venture seeks to expand and check implementation methods designed to make stronger built-in care for speedy breast cancer analysis throughout quite a lot of ranges of the well being care device, specifically for girls presenting with breast signs in number one care settings. This venture will likely be applied inside of Mexico’s public well being device available to the uninsured inhabitants.

“LISTOS will allow us to partner with local health systems to develop laboratories for innovation in cancer screening and early diagnosis and demonstrate both clinical and implementation outcomes that can be replicated nationally in Mexico,” mentioned Michael Potter, MD, with UCSF, who’s co-lead investigator of the colorectal screening learn about and a member of the LISTOS Executive Committee.

The LISTOS Center may be running with Leticia Torres Ibarra, DSc, with INSP; and Olga Martínez, MD, MPH, of the Mexican Institute of Social Security on a pilot venture to learn about implementation of an ongoing program to make stronger human papilloma virus checking out amongst girls running in factories and inns.

“Due to a highly segmented health care model and insufficient evidence on effective implementation strategies, populations in low- to middle-income countries are disproportionately impacted by cancer compared to those in higher-income countries. Our center and the studies we conduct will help address these issues and contribute to the science of implementation in these countries that can be applied to many other health issues,” Unger mentioned.

The NIH investment is below grant U54CA284109.

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